Multiple Sclerosis

	Active	Passive	Assisted Active
Spasicity		*
Muscle Atrophy		*
Motor Functional Impairments	*	*	*
Depression	*	*
Fatigue	*	*

Key Points:

• Current studies demonstrate that physical activity in patients with MS counteracts depression and fatigue and may improve quality of life. Interventional studies have described a reduction of the functional impairment in MS patients.

Studies and White Papers

• Multiple sclerosis and exercise : effects of physical activity on the immune system. https://link.springer.com/article/10.1007%2Fs00115-008-2639-3

• An increasing number of studies have shown beneficial effects of exercise training in MS. It has been reported that such programs not only improve fitness parameters but can also enhance quality of life and beneficially affect some suggestive disability measures. https://www.tandfonline.com/doi/full/10.1586/14737175.6.3.347

• The effect of cycling using active-passive trainers on spasticity, cardiovascular fitness, function and quality of life in people with moderate to severe Multiple Sclerosis (MS); a feasibility study. https://www.sciencedirect.com/science/article/abs/pii/S2211034819302652